Very exiting news - after a very long time since version 2.0, there is a new version 2.4.0 out that also includes a MacOS bundle. In this blog, you will find quite extensive articles about setting up a superior frontend for MAME under MacOS. All should work in this version as well.
At first glance, everything seems to work just as it should, but I will do further thorough testing. It is just great to have an official MacOS release out again.